Blood – Components, their importance……Just refresh your knowledge

Blood is the body fluid which delivers nutrients and oxygent to cells and take out metabolic waste products away from the same cells.

This everybody knows. But questions are varied regarding blood. Here we are presenting some basic facts about human blood that will refresh your knowledge.

– Blood accounts for 7% of body weight

– Average adult blood volume – 5 liters

– Blood is composed of plasma and corpuscles or formed elements

– Different corpuscles or cells are RBC’s or erythrocytes, WBC’s or Leukocytes, Platelets or Thrombocytes

– Blood has 54.3% plasma – 45% whole blood – White cells – 0.7%

– Total RBC count – 4.5 – 5.5million/cmm

– Total WBC Count – 4000 – 11000/cmm

– Total Platelet Count – 2lac – 3lac/cmm

– RBC’s lack nucleus

– Blood Plasma contains 92% water

– Ph value of blood is 7.35 – 7.45

– RBC – Life span – 120 days

How blood is produced?

Blood is produced in bone marrow through process called hematopoesis which include erythropoesis – RBC production, Myelopoiesis – WBC and Platelet production. Clotting proteins of blood is from liver. Hormones in blood from endocrine glands while water in it is from hypothalamus, maintained by kidney.

What are the type of leukocytes or WBC’S?

WBC’s protect body against infectious diseases and foreign pathogens. They are found both in blood and lymphatic system. The five types of WBCs are neutrophis, eosinophils, basophils, lymphocytes and monocytes.

Neutrophils – defend against bacterial and fungal infections

Eosinophils – Deal with parasitic infections

Basophils – Concerned with allergic and antigen response by releasing histamine and dilation of blood vessels

Lymphocytes – Include B cells which makes antibodies which can bind to pathogens, block pathogens, activate complement system and enhance pathogen destruction

– Tcells include CD4 T cells, CD8 T Cells
etc which bind with antigens and destroy them
– Natural killer cells

Monocytes – They are the vaccum cleaners ie phagocytosis function with kidney shaped nucleus

What are the different disorders associated with blood?

Blood Disorders affecting RBCs are called anemias – different types, Polycythemia vera, malaria etc

That affecting WBCs include lymphomas, Leukemias, Mutiple myelomas, Myelodisplastic syndromes etc

That affecting Platelets include Idiopathic Thrombocytopenic Purpura, primary thrombocythemia etc

That affecting plasma include sepsis, hemophilia, von Willebrand disease, Hypercoagulable state, DVTs, Disseminated intravascular coagulation etc.

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September 8th, 2015 by
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